Buy Peptides A team of researchers has created red blood cells that can release therapeutic proteins when illuminated by light. The scientists embedded a peptide, melittin (a component of honey bee venom), into the membranes of human RBCs and modified it so that it only causes the cells to rupture when exposed to a specific wavelength of light. The researchers then loaded the engineered RBCs with thrombin, an enzyme that initiates the blood-clotting process, and showed that the peptide-modified RBCs released the molecule only when illuminated by the chosen wavelength of light.
The peptide was synthesized using a standard solid phase synthesis method and characterized by electrospray ionization mass spectrometry. The purity of the peptide was higher than 92%. Ruijun He and Baichuan Wang are co-first authors.